| Brand Name | Zofran |
| Generic Name | Ondansetron |
| Drug Class | 5HT3 receptor antagonists |
| Availability | Prescription only |
| Manufacturer | GlaxoSmithKline |
| Indications | Zofran blocks the actions of chemicals in the body that can trigger nausea and vomiting. |
| Type | Tablet |
| Doses | 4mg |
| Route | Oral |
| Side Effects | Rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. |
| Interactions | High levels of serotonin to build up in your body, a condition called "serotonin syndrome," |
| Overdose | Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. |
| Missed Dose | Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. |
| Contraindications | Severe constipation, stomach pain, or bloating;headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;fast or pounding heartbeats; |
| Alternatives | Ativan,Reglan |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Although ondansetron is not specifically approved by the FDA to treat nausea and vomiting during pregnancy (NVP), its use is common, and approximately 25% of pregnant women are prescribed ondansetron to treat NVP
If you are taking ondansetron for nausea that occurs with meals, then the standard tablet should be taken half an hour to 1 hour before meals, and the orally disintegrating tablet or oral soluble film can be taken 15 minutes before meals.
Yes, Zofran (ondansetron) can be taken with or without food. However, taking it with a small amount of food may help reduce the risk of mild stomach discomfort.
Zofran is not known to cause drowsiness in most people. However, some individuals may experience dizziness or fatigue as a side effect. Avoid driving or operating heavy machinery if you feel drowsy after taking Zofran.
