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Clenpiq Bowel Preparation

Get a complete Clenpiq bowel prep guide with fasting tips, medication instructions, and step-by-step preparation for a smooth procedure.

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Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
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Video Instructions

Written Instructions

General Instructions

2 Weeks Before the Procedure

Foods No change
Liquids Drink plenty of water
Medications Hold - GLP1 Agonist Medication:
  • Dulaglutide (Trulicity)
  • Exenatide (Byetta)
  • Exenatide Extended Release (Bydureon BCise)
  • Liraglutide (Victoza)
  • Lixisenatide (Adlyxin)
  • Semaglutide (Ozempic, Wegovy, Rybelsus)
  • Tirzepatide (Mounjaro)

1 Week Before the Procedure

Foods

No Nuts or Seeds - berries, cashews, corn nuts, peanuts, pecans, popcorn, walnuts

Low Fiber Diet

  • Foods - white bread, cheese, eggs, yogurt
  • Soups - clear vegetable, chicken or beef broth
  • Vegetables - cooked without skin like mashed potatoes
  • Fruits - pureed fruits without skin like applesauce
Liquids Drink plenty of water
Medications
  • Take as usual unless otherwise instructed
  • Hold - Anti-Diarrheal Medication - Imodium, Kaopectate, Pepto-Bismol
  • Hold - Iron Tablets
  • Hold - Multivitamins
  • Pharmacy
    • Fill or buy preparation medication
    • Pick up 3 days before your procedure

1 Day Before the Procedure

Foods
  • Clear Liquid Diet
  • Soups - clear vegetable, chicken or beef broth
  • Juices - clear only without pulp
Liquids
  • Drink plenty of water
  • No alcohol
  • No red or purple colored drinks
Medications
  • Hold - Oral Diabetes Medication
  • Insulin - Take ½ the dose the entire day
  • Blood Pressure Medication - The pre-anesthesia team (PAT) will instruct you on how to take your blood pressure medications.
  • All other medications - continue as normal

Procedure Day

Foods No Food or liquids the day of the procedure

Medication Instructions

Attention

Expected Symptoms Do not stop the bowel preparation

First Dosage → 4PM - 5PM

Step 1 4PM - 4:30PM

Drink 1st bottle of Clenpiq

Step 2 4:30PM - 5PM

Drink 40 ounces of water

Second Dosage → 10PM - 11PM

Step 1 10PM - 10:30PM

Drink 2nd bottle of Clenpiq

Step 2 10:30PM - 11PM

Drink 40 ounces of water

12AM

Foods No food or liquids after midnight

Frequently Asked Questions

What is the advice for Clenpiq?

Follow your doctor's instructions carefully, stay hydrated, stick to a clear liquid diet, and take the doses at the prescribed times. Expect frequent bowel movements and remain near a bathroom.

Who should not take Clenpiq?

People with kidney disease, severe dehydration, bowel obstruction, toxic megacolon, heart failure, or electrolyte imbalances should avoid Clenpiq. Consult a doctor if pregnant, on diuretics, or have a history of GI disorders.

How long does Clenpiq take to start working?

Clenpiq usually starts working within 30 minutes to 3 hours. Some experience effects sooner, while others may take longer, depending on hydration and digestion. Stay near a bathroom.

What type of bowel prep is Clenpiq?

Clenpiq is a low-volume, stimulant and osmotic laxative bowel prep. It contains sodium picosulfate, magnesium oxide, and citric acid, working to draw water into the intestines for colon cleansing.

Should you drink Clenpiq fast or slow?

Drink Clenpiq slowly over 5 to 10 minutes to avoid nausea. Follow with clear liquids as directed. Drinking too fast may cause bloating, cramping, or discomfort.

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