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Suprep Bowel Preparation

Learn how Suprep effectively cleanses your colon for a successful colonoscopy. Get step-by-step instructions and expert tips for optimal results today!

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Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
Memorial hermann
Houston Methodist leading Medicine
HCA Houston Healthcare

Video Instructions

Written Instructions

General Instructions

2 Weeks Before the Procedure

Foods No change
Liquids Drink plenty of water
Medications Hold - GLP1 Agonist Medication:
  • Dulaglutide (Trulicity)
  • Exenatide (Byetta)
  • Exenatide Extended Release (Bydureon BCise)
  • Liraglutide (Victoza)
  • Lixisenatide (Adlyxin)
  • Semaglutide (Ozempic, Wegovy, Rybelsus)
  • Tirzepatide (Mounjaro)

1 Week Before the Procedure

Foods

No Nuts or Seeds - berries, cashews, corn nuts, peanuts, pecans, popcorn, walnuts

Low Fiber Diet

  • Foods - white bread, cheese, eggs, yogurt
  • Soups - clear vegetable, chicken or beef broth
  • Vegetables - cooked without skin like mashed potatoes
  • Fruits - pureed fruits without skin like applesauce
Liquids Drink plenty of water
Medications
  • Take as usual unless otherwise instructed
  • Hold - Anti-Diarrheal Medication - Imodium, Kaopectate, Pepto-Bismol
  • Hold - Iron Tablets
  • Hold - Multivitamins

Pharmacy

  • Fill or buy preparation medication
  • Pick up 3 days before your procedure

1 Day Before the Procedure

Foods
  • Clear Liquid Diet
  • Soups - clear vegetable, chicken or beef broth
  • Juices - clear only without pulp
Liquids
  • Drink plenty of water
  • No alcohol
  • No red or purple colored drinks
Medications
  • Hold - Oral Diabetes Medication
  • Insulin - Take ½ the dose the entire day
  • Blood Pressure Medication - The pre-anesthesia team (PAT) will instruct you on how to take your blood pressure medications.
  • All other medications - continue as normal

Procedure Day

Foods No - Food or liquids the day of the procedure

Medication Instructions

Attention

Expected Symptoms Do not stop the bowel preparation
  • Abdominal Pain
  • Bloating
  • Cramps
  • Diarrhea
  • Gas
  • Nausea

First Dosage → 4PM - 5:30PM

Step 1 4PM - 04:30PM
  • Mix first 6 ounce bottle of Suprep & 10 ounces of water into the provided container
  • Drink 16 ounces of solution
Step 2 4:30PM - 5PM

Drink 16 ounces of solution

Step 3 5PM - 05:30PM

Drink 16 ounces of water

Second Dosage → 10PM - 11:30PM

Step 1 10PM - 10:30PM
  • Mix second 6 ounce bottle of Suprep & 10 ounces of water into the provided container
  • Drink 16 ounces of solution
Step 2 10:30PM - 11PM

Drink 16 ounces of water

Step 3 11PM - 11:30PM

Drink 16 ounces of water

12AM

Foods No food or liquids after midnight

Frequently Asked Questions

When should I start prep for a 12 PM colonoscopy?

Start prep the evening before, around 5-7 PM, with the first dose. Take the second dose 5-6 hours before the procedure, around 6-7 AM, following doctor's instructions.

What are the warning precautions for Suprep?

Avoid Suprep if you have kidney disease, heart failure, bowel obstruction, or severe dehydration. Stay hydrated, monitor for electrolyte imbalances, and follow dosage instructions carefully.

What time to start Suprep?

Typically, the first dose is taken the evening before the colonoscopy, around 5-7 PM. The second dose is taken 4-6 hours before the procedure, usually early morning.

What should you eat before Suprep?

Stick to a low-fiber diet a few days before, then switch to a clear liquid diet the day before. Drink broth, clear juices, tea, and sports drinks. Avoid dairy and red or purple liquids.

When does Suprep start working?

Everyone has a different response to the bowel prep solution. Some people start having diarrhea within an hour of drinking the solution. Others have no response for a few hours.

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