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Clenpiq Bowel Preparation

Learn the best way to use Clenpiq for an afternoon colonoscopy. Get step-by-step instructions for effective colon cleansing.

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Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
Memorial hermann
Houston Methodist leading Medicine
HCA Houston Healthcare

Video Instructions

Written Instructions

General Instructions

2 Weeks Before the Procedure

Foods No change
Liquids Drink plenty of water
Medications Hold - GLP1 Agonist Medication:
  • Dulaglutide (Trulicity)
  • Exenatide (Byetta)
  • Exenatide Extended Release (Bydureon BCise)
  • Liraglutide (Victoza)
  • Lixisenatide (Adlyxin)
  • Semaglutide (Ozempic, Wegovy, Rybelsus)
  • Tirzepatide (Mounjaro)

1 Week Before the Procedure

Foods

No Nuts or Seeds - berries, cashews, corn nuts, peanuts, pecans, popcorn, walnuts

Low Fiber Diet

  • Foods - white bread, cheese, eggs, yogurt
  • Soups - clear vegetable, chicken or beef broth
  • Vegetables - cooked without skin like mashed potatoes
  • Fruits - pureed fruits without skin like applesauce
Liquids Drink plenty of water
Medications
  • Take as usual unless otherwise instructed
  • Hold - Anti-Diarrheal Medication - Imodium, Kaopectate, Pepto-Bismol
  • Hold - Iron Tablets
  • Hold - Multivitamins

Pharmacy

  • Fill or buy preparation medication
  • Pick up 3 days before your procedure

1 Day Before the Procedure

Foods
  • Clear Liquid Diet
  • Soups - clear vegetable, chicken or beef broth
  • Juices - clear only without pulp
Liquids
  • Drink plenty of water
  • No alcohol
  • No red or purple colored drinks
Medications
  • Hold - Oral Diabetes Medication
  • Insulin - Take ½ the dose the entire day
  • Blood Pressure Medication - The pre-anesthesia team (PAT) will instruct you on how to take your blood pressure medications.
  • All other medications - continue as normal

Procedure Day

Foods No Food or liquids the day of the procedure

Medication Instructions

Attention

Expected Symptoms Do not stop the bowel preparation
  • Abdominal Pain
  • Bloating
  • Cramps
  • Diarrhea
  • Gas
  • Nausea

First Dosage → 10PM - 11PM

Step 1 10PM - 10:30PM

Drink 1st bottle of Clenpiq

Step 2 10:30PM - 11PM

Drink 40 ounces of water

Second Dosage → 4AM - 5AM

Step 1 4AM - 4:30AM

Drink 2nd bottle of Clenpiq

Step 2 4:30AM - 5AM

Drink 40 ounces of water

12AM

Foods No food or liquids after midnight except prep solution

Frequently Asked Questions

When should I start preparing for afternoon colonoscopy?

If your procedure is scheduled for 12 p.m., you should not eat any solid food after midnight the night before but can have clear liquids until 9 a.m. of the day of the procedure.

Which is better, Clenpiq or Sutab?

Clenpiq is a low-volume liquid prep, while Sutab is a tablet-based prep. Clenpiq may be easier to drink, but Sutab avoids bad taste. Effectiveness depends on patient preference and tolerance.

How bad does Clenpiq taste?

Clenpiq has a sweet, citrus-like taste but can be strong and slightly bitter. Chilling it, using a straw, or rinsing with clear liquid can help with the taste.

When should I start prep for Before noon colonoscopy?

Start the first dose the night before around 10PM - 11PM , and take the second dose early morning, around 4AM - 5AM, ensuring it's 5-6 hours before the procedure.

Can I drink water right after Clenpiq?

Yes, you should drink at least 5 cups of clear liquid after each dose to stay hydrated and help the prep work effectively. Avoid red, purple, or dairy-based liquids.

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