| Brand Name | Reglan |
| Generic Name | Metoclopramide |
| Drug Class | Prokinetic agent; Antiemetic |
| Availability | Prescription only |
| Manufacturer | A.H. Robins |
| Indications | Diabetic gastroparesis Gastroesophageal reflux disease (GERD) Prevention of nausea and vomiting associated with chemotherapy or surgery Facilitation of small bowel intubation and radiologic examinations |
| Type | Tablet |
| Doses | 10 mg |
| Route | Oral |
| Side Effects | Drowsiness Fatigue Restlessness Extrapyramidal symptoms (e.g., tremors, involuntary movements) Tardive dyskinesia (with long-term use) Depression |
| Interactions | May enhance the effects of alcohol and other CNS depressants Can interact with antipsychotic medications, increasing the risk of extrapyramidal symptoms May affect the absorption of drugs such as digoxin and cyclosporine |
| Overdose | Drowsiness Disorientation Extrapyramidal reactions Seizures |
| Missed Dose | Take as soon as remembered unless it's close to the next dose |
| Contraindications | Known hypersensitivity to metoclopramide Gastrointestinal bleeding, obstruction, or perforation Pheochromocytoma History of tardive dyskinesia or other extrapyramidal symptoms |
| Alternatives | Domperidone (Note: Not approved in the U.S.) Erythromycin (used off-label for gastroparesis) Prochlorperazine (for nausea and vomiting) |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
A: Yes, long-term or high-dose use can lead to tardive dyskinesia, a serious movement disorder.
A: Reglan is sometimes used during pregnancy for severe nausea, but it should only be taken under medical supervision.
