| Brand Name | Questran |
| Generic Name | Cholestyramine |
| Drug Class | Bile Acid Sequestrant |
| Availability | Prescription only |
| Manufacturer | Bristol-Myers Squibb |
| Indications | Primary hypercholesterolemia (high cholesterol) Relief of pruritus (itching) associated with partial biliary obstruction Management of diarrhea associated with bile acid malabsorption |
| Type | Tablet |
| Doses | 4 grams |
| Route | Oral |
| Side Effects | Constipation Bloating Gas Abdominal discomfort Nausea Heartburn Increased risk of bleeding due to vitamin K deficiency with long-term use |
| Interactions | Warfarin Thiazide diuretics Propranolol Digoxin Fat-soluble vitamins (A, D, E, K) |
| Overdose | Severe constipation Intestinal obstruction |
| Missed Dose | Take as soon as remembered unless it's close to the next dose |
| Contraindications | Complete biliary obstruction Hypersensitivity to cholestyramine or any component of the formulation |
| Alternatives | Other bile acid sequestrants, such as colestipol and colesevelam Statins or other lipid-lowering agents, depending on the condition being treated |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
A: Questran can interfere with the absorption of certain medications. It is recommended to take other medications at least 1 hour before or 4 to 6 hours after taking Questran.
A: Mix the prescribed amount of Questran powder with water or a non-carbonated beverage and drink immediately. Follow your healthcare provider's instructions regarding dosage and timing.
