| Brand Name | Purinethol |
| Generic Name | Mercaptopurine |
| Drug Class | Antimetabolite, Immunosuppressant |
| Availability | Prescription only |
| Manufacturer | Burroughs Wellcome |
| Indications | Acute lymphocytic leukemia (ALL) Crohn's disease Ulcerative colitis |
| Type | Tablet |
| Doses | as directed by your healthcare provider |
| Route | Oral |
| Side Effects | Bone marrow suppression (leading to anemia, leukopenia, thrombocytopenia) Liver toxicity Nausea Vomiting Loss of appetite Increased susceptibility to infections |
| Interactions | Allopurinol, Warfarin Live vaccines |
| Overdose | Severe bone marrow suppression Bleeding Infections Gastrointestinal disturbances |
| Missed Dose | Take as soon as remembered unless it's close to the next dose |
| Contraindications | Should not be used in patients who have a hypersensitivity to mercaptopurine or any component of the formulation |
| Alternatives | Azathioprine (Imuran) Methotrexate Biologic agents (e.g., infliximab, adalimumab) |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
A: Mercaptopurine may harm an unborn baby. Discuss with your healthcare provider if you are pregnant or planning to become pregnant.
A: Store at room temperature away from moisture and heat.
